Haemodialysis (HD) is a life-saving therapy for individuals with kidney failure. Post-filter haemodiafiltration (HDF) and high-flux HD are among the most widely used treatment modalities of kidney failure. To date, 10 randomized controlled trials (RCTs) have compared all-cause and cardiovascular (CV) mortality between pre- or post-filter HDF and low- or high-flux HD in adults undergoing maintenance dialysis for at least 1 year [1–10].
On the fragility of outcome measures of two individual patient data analyses from randomized controlled trials on online haemodiafiltration
Mantovani, Alessandro;Battaglia, Yuri
2025-01-01
Abstract
Haemodialysis (HD) is a life-saving therapy for individuals with kidney failure. Post-filter haemodiafiltration (HDF) and high-flux HD are among the most widely used treatment modalities of kidney failure. To date, 10 randomized controlled trials (RCTs) have compared all-cause and cardiovascular (CV) mortality between pre- or post-filter HDF and low- or high-flux HD in adults undergoing maintenance dialysis for at least 1 year [1–10].
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