Interdental Papilla Regeneration with Hyaluronic Acid: a Narrative Review

Peri-implantitis is a growing concern as dental implants become increasingly popular. This review paper aims to present the current understanding of peri-implant disease and provide insights into its management and prevention. The study followed PRISMA guidelines and conducted an extensive electronic search for relevant articles. Only systematic reviews published in Q1 and Q2 journals were considered. Eighteen systematic reviews have been selected from the 63 initial studies. The prevalence of peri-implantitis is estimated at around 19.53% of patients with implants and 12.53% of implants placed. Specific bacteria and MMP-8 levels have been associated with peri-implantitis, highlighting potential diagnostic markers. The review emphasized the need for consensus in research to accurately estimate the epidemiological parameters of peri-implantitis. Additionally, the adjunctive use of local antibiotics showed promising results in improving probing pocket depth and bleeding on probing compared to surgical treatment alone. Overall, this paper provides a comprehensive overview of the current knowledge on peri- implantitis and emphasizes the importance of precise diagnostic markers and effective treatment modalities.