The NLR ratio is a low-cost test (an easy calculation that can be performed manually or even automatically set within the laboratory information system), that is available in almost all clinical facilities with a basic hematological analyzer. This parameter has proven useful in a wide range of human pathologies, including acute coronary syndrome and COVID-19. On this premise, a further step must be taken to provide some reliable answers to 3 basic questions: “why does the NLR ratio increase in patients with cardiovascular disease?” and “is this parameter sufficiently standardized?” and, finally, “how should we use this information in the managed care of our patients?”. In summary, the NLR ratio seems a cost-effective parameter for diagnosis and prognosis of myocardial ischemia, but several other aspects still need to be clarified before it becomes suitable for routine clinical use.
Neutrophil-to-lymphocyte ratio in acute coronary syndromes: Do we (really) need another hero?
Lippi, Giuseppe
;
2024-01-01
Abstract
The NLR ratio is a low-cost test (an easy calculation that can be performed manually or even automatically set within the laboratory information system), that is available in almost all clinical facilities with a basic hematological analyzer. This parameter has proven useful in a wide range of human pathologies, including acute coronary syndrome and COVID-19. On this premise, a further step must be taken to provide some reliable answers to 3 basic questions: “why does the NLR ratio increase in patients with cardiovascular disease?” and “is this parameter sufficiently standardized?” and, finally, “how should we use this information in the managed care of our patients?”. In summary, the NLR ratio seems a cost-effective parameter for diagnosis and prognosis of myocardial ischemia, but several other aspects still need to be clarified before it becomes suitable for routine clinical use.
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