Oxalate is both a plant-derived molecule and a terminal toxic metabolite with no known physiological function in humans. It is predominantly eliminated by the kidneys through glomerular filtration and tubular secretion. Regardless of the cause, the increased load of dietary oxalate presented to the kidneys has been linked to different kidney-related conditions and injuries, including calcium oxalate nephrolithiasis, acute and chronic kidney disease. In this paper, we review the current literature on the association between dietary oxalate intake and kidney outcomes.

Dietary oxalate intake and kidney outcomes

Ferraro P. M.
2020-01-01

Abstract

Oxalate is both a plant-derived molecule and a terminal toxic metabolite with no known physiological function in humans. It is predominantly eliminated by the kidneys through glomerular filtration and tubular secretion. Regardless of the cause, the increased load of dietary oxalate presented to the kidneys has been linked to different kidney-related conditions and injuries, including calcium oxalate nephrolithiasis, acute and chronic kidney disease. In this paper, we review the current literature on the association between dietary oxalate intake and kidney outcomes.
2020
Acute kidney injury
Chronic kidney disease
Diet
Nephrocalcinosis
Nephrolithiasis
Oxalate
Animals
Diet
Disease Models
Animal
Glomerular Filtration Rate
Humans
Kidney
Nephrolithiasis
Oxalates
Randomized Controlled Trials as Topic
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1115320
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