Reactivation of the varicella-zoster virus (VZV) along the sensory nerves innervating the ear, including the geniculate ganglion, is responsible for herpes zoster oticus (HZO). In some cases, HZO is associated with polyneuropathy of the cranial nerves, although the mechanism of this involvement is not known. To explain this phenomenon and based on some clinical considerations, the present authors hypothesize an intersynaptic spread of VZV along the reflex pathways of the brainstem

Herpes zoster oticus: a clinical model for a transynaptic, reflex pathways, viral transmission hypotheses

MONZANI, Daniele;
2012-01-01

Abstract

Reactivation of the varicella-zoster virus (VZV) along the sensory nerves innervating the ear, including the geniculate ganglion, is responsible for herpes zoster oticus (HZO). In some cases, HZO is associated with polyneuropathy of the cranial nerves, although the mechanism of this involvement is not known. To explain this phenomenon and based on some clinical considerations, the present authors hypothesize an intersynaptic spread of VZV along the reflex pathways of the brainstem
2012
Brain Stem
Cranial Nerves
Herpes Zoster Oticus
Herpesvirus 3
Human
Humans
Reflex
Synapses
Virus Activation
Models
Biological
Neural Pathways
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1112154
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