The impact of biologic therapy for moderate-to-severe psoriasis on the immune responses to SARS-CoV2 infection and vaccination

Dear Editor, we explored the impact of biologics and conventional therapies for psoriasis on humoral and T-cellular responses to SARS-CoV-2 infection and vaccine. The study (EUDRA 2020-004965-37 Humanitas ICH Ethic Committee) was conducted at the Istituto Clinico Humanitas-Rozzano, Milan, and at the University of Verona, Italy. The enrolled patients were affected by moderate-to-severe psoriasis and were divided into two groups: those who had developed COVID-19 infection (group 1, n=95) and those who underwent COVID-19 vaccination (group 2, n=77)