This paper introduces conjugate word blending as a formal model of molecular processes that occur during a DNA experimental protocol called cross-pairing Polymerase Chain Reaction (XPCR). We analyze this formal word and language operation from a computational viewpoint, by investigating closure properties of four Chomsky language families under it. We also report the molecular biology wet lab experiments based on XPCR amplification of gene sequences, which led to the notion of conjugate word blending.

Conjugate word blending: formal model and experimental implementation by XPCR

Bellamoli, F.;Franco, G.;Lampis, S.;
2021-01-01

Abstract

This paper introduces conjugate word blending as a formal model of molecular processes that occur during a DNA experimental protocol called cross-pairing Polymerase Chain Reaction (XPCR). We analyze this formal word and language operation from a computational viewpoint, by investigating closure properties of four Chomsky language families under it. We also report the molecular biology wet lab experiments based on XPCR amplification of gene sequences, which led to the notion of conjugate word blending.
2021
Conjugate word blending
Cross-pairing Polymerase Chain Reaction (XPCR)
DNA computing
Gene assembly
Formal language operations
Molecular computing
Word blending
Word operations
File in questo prodotto:
File Dimensione Formato  
Bellamoli2021_Article_ConjugateWordBlendingFormalMod.pdf

solo utenti autorizzati

Licenza: Non specificato
Dimensione 730.42 kB
Formato Adobe PDF
730.42 kB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1096166
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus 0
  • ???jsp.display-item.citation.isi??? 0
social impact