The prevalences and distributions of NOSAs appear to be age-independent, with the notable exception of LKM1, which occurs predominately in children. We are, therefore, unable to explain the higher prevalence of SMA (67%) reported by Gregorio et al. [4]. We suppose that the insufficient standardization of the indirect immunofluorescence technique commonly used for NOSA detection may account, at least in part, for this discrepancy; making available reference serum samples for sharing between different laboratories would be an important step to reduce the operator-dependent bias.
Non-organ-specific autoantibodies in children with chronic hepatitis C virus infection [3] (multiple letters)
Davide Gibellini;
2004-01-01
Abstract
The prevalences and distributions of NOSAs appear to be age-independent, with the notable exception of LKM1, which occurs predominately in children. We are, therefore, unable to explain the higher prevalence of SMA (67%) reported by Gregorio et al. [4]. We suppose that the insufficient standardization of the indirect immunofluorescence technique commonly used for NOSA detection may account, at least in part, for this discrepancy; making available reference serum samples for sharing between different laboratories would be an important step to reduce the operator-dependent bias.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
