Changes induced by metabolic surgery on the main components of glucose/insulin system in patients with diabetes and obesity

Bariatric surgery is able to induce remission of type 2 diabetes (T2D). Several studies reported an improvement of insulin sensitivity after surgery [1], but data about insulin secretion and insulin clearance are less abundant and somewhat controversial. Aim of our study was to assess the changes of the determinants of glucose regulation, i.e., insulin secretion, insulin sensitivity and insulin clearance in a group of T2D patients with obesity one month and over 1 year after metabolic surgery.