Dear Editor, There are between 450 and 750 minor salivary glands distributed in the upper aerodigestive tract, in the palate, lips, paranasal sinuses and nasal cavity, tongue, floor of mouth, gingiva, pharynx, larynx and trachea [1]. About 80–90% of neoplasms that grow in these glands are malignant. Minor salivary gland carcinomas (MSGCs) comprise a heterogeneous group of malignancies whose etiologies are unknown [2]. Adenoid cystic carcinoma is the most common, while mucoepidermoid carcinoma is the second, with these two tumors comprising most of all neoplasms [3]. The most common site of MSGCs is the palate, with an incidence of 8–22% among all epithelial salivary gland tumors
The role of the depth of invasion (DOI) in minor salivary glands tumors according to the 8th TNM classification: Pitfalls and potential misinterpretations
Nocini, Riccardo;Gazzini, Luca;Dallari, Virginia;Girolami, Ilaria;
2022-01-01
Abstract
Dear Editor, There are between 450 and 750 minor salivary glands distributed in the upper aerodigestive tract, in the palate, lips, paranasal sinuses and nasal cavity, tongue, floor of mouth, gingiva, pharynx, larynx and trachea [1]. About 80–90% of neoplasms that grow in these glands are malignant. Minor salivary gland carcinomas (MSGCs) comprise a heterogeneous group of malignancies whose etiologies are unknown [2]. Adenoid cystic carcinoma is the most common, while mucoepidermoid carcinoma is the second, with these two tumors comprising most of all neoplasms [3]. The most common site of MSGCs is the palate, with an incidence of 8–22% among all epithelial salivary gland tumors
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