Several not-yet fully described neutrophil populations exerting either antitumor or suppressive/protumor functions may appear in the circulation of patients with cancer and/or infiltrate tumor tissues. In this issue, Emmons and colleagues provide new information on how complement-dependent "activation" of normal mature neutrophils renders the cells able to inhibit T-cell responsiveness in vitro. The data highlight the complexities of understanding the biology of neutrophil-mediated T-cell suppression.

Characterizing the Complexities of Neutrophils with Suppressive Properties

Cassatella, Marco Antonio
2021

Abstract

Several not-yet fully described neutrophil populations exerting either antitumor or suppressive/protumor functions may appear in the circulation of patients with cancer and/or infiltrate tumor tissues. In this issue, Emmons and colleagues provide new information on how complement-dependent "activation" of normal mature neutrophils renders the cells able to inhibit T-cell responsiveness in vitro. The data highlight the complexities of understanding the biology of neutrophil-mediated T-cell suppression.
Humans
T-Lymphocytes
Neoplasms
Neutrophils
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/1060305
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