We tested the vagal withdrawal concept for heart rate (HR) and cardiac output (CO) kinetics upon moderate exercise onset, by analysing the effects of vagal blockade on cardiovascular kinetics in humans. We hypothesized that, under atropine, the φ1 amplitude (A1) for HR would reduce to nil, whereas the A1 for CO would still be positive, due to the sudden increase in stroke volume (SV) at exercise onset.

Vagal blockade suppresses the phase I heart rate response but not the phase I cardiac output response at exercise onset in humans

Tam, Enrico;
2021

Abstract

We tested the vagal withdrawal concept for heart rate (HR) and cardiac output (CO) kinetics upon moderate exercise onset, by analysing the effects of vagal blockade on cardiovascular kinetics in humans. We hypothesized that, under atropine, the φ1 amplitude (A1) for HR would reduce to nil, whereas the A1 for CO would still be positive, due to the sudden increase in stroke volume (SV) at exercise onset.
Cardiac output
Exercise transients
Heart rate
Stroke volume
atropine
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/1047385
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