In order to evaluate the efficacy of LEV in pharmacoresistant continuous spikes and waves during slow sleep (CSWS) we tested its efficacy and safety in 16 children with CSWS affected by partial epilpesy of different nature (7 symptomatic, 6 cryptogenic, 3 idiopathic) at the dose of 25-50 mg/Kg/die for a period of 2 months to 3 years. Following the good results (disappearance of EEG abnormalities both at wake and during sleep in 4 cases (25%), their reduction to more that 50% in 5 (31.5%) and the low rate of adverse events (3 drop out cases) the AA stress the possible effectiveness of LEV in children with CSWS.
Efficacy of Levetiracetam in treatment of continous spike wave during sleep (CSWS),Efficacia del Levetiracetam nel trattamento dello stato di punta onda continua del sonno (POCS)
Darra, F.;Zoccante, L.;Fontana, E.;
2004-01-01
Abstract
In order to evaluate the efficacy of LEV in pharmacoresistant continuous spikes and waves during slow sleep (CSWS) we tested its efficacy and safety in 16 children with CSWS affected by partial epilpesy of different nature (7 symptomatic, 6 cryptogenic, 3 idiopathic) at the dose of 25-50 mg/Kg/die for a period of 2 months to 3 years. Following the good results (disappearance of EEG abnormalities both at wake and during sleep in 4 cases (25%), their reduction to more that 50% in 5 (31.5%) and the low rate of adverse events (3 drop out cases) the AA stress the possible effectiveness of LEV in children with CSWS.
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