Beta-amyloid precursor protein (βAPP) is mainly known as the precursor of the fibrillogenic Aβ peptide which forms the amyloid deposits in the Alzheimer’s disease. βAPP has also been demonstrated to be the most reliable marker of axonal damage in the Neuropathological diagnostic practice. Nevertheless, βAPP immunohistochemistry is not widely adopt in the Forensic setting
ΒAPP IMMUNOHISTOCHEMISTRY IN BRAIN TRAUMA: SHOULD IT BE OR NOT BE PERFORMED?
Michela Colombari
;Stefania Turrina;Domenico De Leo
2021-01-01
Abstract
Beta-amyloid precursor protein (βAPP) is mainly known as the precursor of the fibrillogenic Aβ peptide which forms the amyloid deposits in the Alzheimer’s disease. βAPP has also been demonstrated to be the most reliable marker of axonal damage in the Neuropathological diagnostic practice. Nevertheless, βAPP immunohistochemistry is not widely adopt in the Forensic setting
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