Peroxynitrite (ONOO-) is a reactive nitrogen species formed when nitric oxide (NO) reacts with the superoxide anion (O-2(-)). It was first identified as a mediator of cell death in animals but was later shown to act as a positive regulator of cell signaling, mainly through the posttranslational modification of proteins by tyrosine nitration. In plants, peroxynitrite is not involved in NO-mediated cell death and its physiological function is poorly understood. However, it is emerging as a potential signaling molecule during the induction of defense responses against pathogens and this could be mediated by the selective nitration of tyrosine residues in a small number of proteins. In this review we discuss the general role of tyrosine nitration in plants and evaluate recent evidence suggesting that peroxynitrite is an effector of NO-mediated signaling following pathogen infection. (C) 2011 Elsevier Ireland Ltd. All rights reserved.

Peroxynitrite formation and function in plants

Vandelle, E.;Delledonne, M.
2011-01-01

Abstract

Peroxynitrite (ONOO-) is a reactive nitrogen species formed when nitric oxide (NO) reacts with the superoxide anion (O-2(-)). It was first identified as a mediator of cell death in animals but was later shown to act as a positive regulator of cell signaling, mainly through the posttranslational modification of proteins by tyrosine nitration. In plants, peroxynitrite is not involved in NO-mediated cell death and its physiological function is poorly understood. However, it is emerging as a potential signaling molecule during the induction of defense responses against pathogens and this could be mediated by the selective nitration of tyrosine residues in a small number of proteins. In this review we discuss the general role of tyrosine nitration in plants and evaluate recent evidence suggesting that peroxynitrite is an effector of NO-mediated signaling following pathogen infection. (C) 2011 Elsevier Ireland Ltd. All rights reserved.
2011
Peroxynitrite
Tyrosine nitration
Plant
Defense response
Signaling
Models, Biological
Nitric Oxide
Peroxynitrous Acid
Plants
Reactive Nitrogen Species
Signal Transduction
Stress, Physiological
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1040181
Citazioni
  • ???jsp.display-item.citation.pmc??? 37
  • Scopus 127
  • ???jsp.display-item.citation.isi??? 120
social impact