Excess mortality associated with progression rate in asymptomatic aortic valve stenosis

Aortic valve stenosis (AS) is a progressive condition characterized by gradual calcification of the aortic cusps. Progression-rate evaluated by echocardiography has been associated with survival. However, data from routine practice, covering the whole spectrum of AS severity and the rate of symptoms onset are sparse. We aimed to assess the outcome under medical management related to the disease progression in asymptomatic patients with a wide range of AS severity.