In this review, we focused on original manuscripts published in the 2017 that provided additional information on the clinical and therapeutic features of the chronic obstructive pulmonary disease (COPD). We have chosen eight of these studies, collected in four topics concerning the pharmacological treatment (tiotropium) of mild-moderate patients, the pharmacological (fluticasone furoate/vilanterol/umeclidinium) and non-pharmacological treatment (non-invasive mechanical ventilation) of severe patients, the etiology of acute exacerbation of COPD involving seasonal airway pathogens and the role of eosinophils with particular interest to the monoclonal antibody directed against interleukin-5 (mepolizumab). For each topic, we report a brief description of studies, take-home messages, and brief comments.

COPD 2017: A Year in Review

Crisafulli, E;
2018-01-01

Abstract

In this review, we focused on original manuscripts published in the 2017 that provided additional information on the clinical and therapeutic features of the chronic obstructive pulmonary disease (COPD). We have chosen eight of these studies, collected in four topics concerning the pharmacological treatment (tiotropium) of mild-moderate patients, the pharmacological (fluticasone furoate/vilanterol/umeclidinium) and non-pharmacological treatment (non-invasive mechanical ventilation) of severe patients, the etiology of acute exacerbation of COPD involving seasonal airway pathogens and the role of eosinophils with particular interest to the monoclonal antibody directed against interleukin-5 (mepolizumab). For each topic, we report a brief description of studies, take-home messages, and brief comments.
2018
chronic obstructive pulmonary disease
pharmacological treatment
non-invasive mechanical ventilation
acute exacerbation of COPD
eosinophils
Androstadienes
Antibodies, Monoclonal, Humanized
Benzyl Alcohols
Bronchodilator Agents
Chlorobenzenes
Common Cold
Disease Progression
Drug Combinations
Eosinophils
Glucocorticoids
Haemophilus Infections
Humans
Interleukin-5
Moraxellaceae Infections
Muscarinic Antagonists
Noninvasive Ventilation
Pulmonary Disease, Chronic Obstructive
Quinuclidines
Seasons
Severity of Illness Index
Tiotropium Bromide
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1030244
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