The results of our study further highlight the concept that serology testing should not be used as a surrogate for direct RNA identification in diagnosing acute SARS-CoV-2 infection, especially at ED evaluation. Relying on serology by assaying either IgA or IgG would generate an unacceptable number of false negative test results, which may contribute to the risk of propagating COVID-19 within healthcare facilities.
Assessment of immune response against SARS-CoV-2 at emergency department evaluation in COVID-19 patients
Lippi, Giuseppe;
2020-01-01
Abstract
The results of our study further highlight the concept that serology testing should not be used as a surrogate for direct RNA identification in diagnosing acute SARS-CoV-2 infection, especially at ED evaluation. Relying on serology by assaying either IgA or IgG would generate an unacceptable number of false negative test results, which may contribute to the risk of propagating COVID-19 within healthcare facilities.
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