Although further evidence, based on solid cost-effectiveness analyses, would be needed to make definitive conclusions on this matter, it is undeniable that routine D-dimer measurement may currently help identifying a subset of COVID-19 patients at enhanced risk of unfavorable progression, who may then benefit from more extensive assessment and tailored treatment. The ideal cut-off for use in patient stratification needs more definitive investigation, and may differ according to the method used. In theory, there are also 28 possible reporting units for D-dimer, though the number is likely closer to 5 for units preferred by the major D-dimer manufacturers. Irrespective, D-dimer reporting in the COVID-19 era remains problematic, and we hope that future studies will clearly identify what methods and units are being reported, in order to enable clearer comparison of findings.
|Titolo:||D-dimer measurement in COVID-19: Silver bullet or clinical distraction?|
LIPPI, Giuseppe (Corresponding)
|Data di pubblicazione:||2020|
|Appare nelle tipologie:||01.01 Articolo in Rivista|