Although further evidence, based on solid cost-effectiveness analyses, would be needed to make definitive conclusions on this matter, it is undeniable that routine D-dimer measurement may currently help identifying a subset of COVID-19 patients at enhanced risk of unfavorable progression, who may then benefit from more extensive assessment and tailored treatment. The ideal cut-off for use in patient stratification needs more definitive investigation, and may differ according to the method used. In theory, there are also 28 possible reporting units for D-dimer, though the number is likely closer to 5 for units preferred by the major D-dimer manufacturers. Irrespective, D-dimer reporting in the COVID-19 era remains problematic, and we hope that future studies will clearly identify what methods and units are being reported, in order to enable clearer comparison of findings.
D-dimer measurement in COVID-19: Silver bullet or clinical distraction?
Lippi, Giuseppe
;
2020-01-01
Abstract
Although further evidence, based on solid cost-effectiveness analyses, would be needed to make definitive conclusions on this matter, it is undeniable that routine D-dimer measurement may currently help identifying a subset of COVID-19 patients at enhanced risk of unfavorable progression, who may then benefit from more extensive assessment and tailored treatment. The ideal cut-off for use in patient stratification needs more definitive investigation, and may differ according to the method used. In theory, there are also 28 possible reporting units for D-dimer, though the number is likely closer to 5 for units preferred by the major D-dimer manufacturers. Irrespective, D-dimer reporting in the COVID-19 era remains problematic, and we hope that future studies will clearly identify what methods and units are being reported, in order to enable clearer comparison of findings.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.