In patients with eosinophilic granulomatosis with polyangiitis in remission phase and persisting severe steroid-dependent asthma, mepolizumab 100 mg/4 wk prevents vasculitis relapse and maintains asthma control. An “asthma-tailored” dose may be considered in the maintenance phase of eosinophilic granulomatosis with polyangiitis as a steroid/immunosuppressive-sparing agent.
Mepolizumab 100 mg in severe asthmatic patients with EGPA in remission phase
Caminati, Marco;Crisafulli, Ernesto;Lunardi, Claudio;Micheletto, Claudio;Festi, Giuliana;Maule, Matteo;Giollo, Alessandro;Orsolini, Giovanni;Senna, Gianenrico
2021-01-01
Abstract
In patients with eosinophilic granulomatosis with polyangiitis in remission phase and persisting severe steroid-dependent asthma, mepolizumab 100 mg/4 wk prevents vasculitis relapse and maintains asthma control. An “asthma-tailored” dose may be considered in the maintenance phase of eosinophilic granulomatosis with polyangiitis as a steroid/immunosuppressive-sparing agent.
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