Herein we report the formation and characterization of a novel type of capsules resulting from the self-association between oppositely charged complementary building blocks in MeOH/H2O. The assembly is based on the interaction between tetraamidinium calixarenes 1a-d and tetrasulfonato calixarene 2. Evidence for the formation of the expected 1:1 assemblies is provided by proton NMR, ESI-MS, and ITC. The association process is fast on the NMR time scale and strongly entropy driven, with association constants in the range of 10(6) M-1. The system 1a.2 shows binding affinity toward acetylcholine, tetramethylammonium, and N-methylquinuclidinium cations.
|Titolo:||Guest encapsulation and self-assembly of molecular capsules in polar solvents via multiple ionic interactions|
|Data di pubblicazione:||2002|
|Appare nelle tipologie:||01.01 Articolo in Rivista|