Corona-Score displays lower AUC (0.74 vs. 0.91) and sensitivity (82% vs. 96%), but slightly higher specificity (96% vs. 95%) in our US cohort of patients seeking ED care compared to a Dutch cohort, which may be at least in part attributable to the different demographic characteristics of our population, the different organization of the national healthcare system and the care access in the US. While it seems unlikely that this scoring system would offer such a high diagnostic accuracy to completely replace NAATs, it may still serve as practical adjunct for adjusting pre- and post-test probabilities. Moreover, it may prove an important tool for screening of sick control groups in COVID-19 clinical studies.
Validation of the Corona-Score for rapid identification of SARS-CoV-2 infections in patients seeking emergency department care in the United States
Lippi, Giuseppe
;
2020-01-01
Abstract
Corona-Score displays lower AUC (0.74 vs. 0.91) and sensitivity (82% vs. 96%), but slightly higher specificity (96% vs. 95%) in our US cohort of patients seeking ED care compared to a Dutch cohort, which may be at least in part attributable to the different demographic characteristics of our population, the different organization of the national healthcare system and the care access in the US. While it seems unlikely that this scoring system would offer such a high diagnostic accuracy to completely replace NAATs, it may still serve as practical adjunct for adjusting pre- and post-test probabilities. Moreover, it may prove an important tool for screening of sick control groups in COVID-19 clinical studies.
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