The possibility of bloodstream infections caused by 3rd-generation cephalosporin-resistant Enterobacterales (3GC-R-BSI) leads to a trade-off between empiric inappropriate treatment (IAT) and unnecessary carbapenem use (UCU). Accurately predicting 3GC-R-BSI could reduce IAT and UCU. We externally validate two previously derived prediction rules for community-onset (CO) and hospital-onset (HO) suspected bloodstream infections.
An International Prospective Cohort Study To Validate 2 Prediction Rules for Infections Caused by Third-generation Cephalosporin-resistant Enterobacterales
Tacconelli, Evelina;
2021-01-01
Abstract
The possibility of bloodstream infections caused by 3rd-generation cephalosporin-resistant Enterobacterales (3GC-R-BSI) leads to a trade-off between empiric inappropriate treatment (IAT) and unnecessary carbapenem use (UCU). Accurately predicting 3GC-R-BSI could reduce IAT and UCU. We externally validate two previously derived prediction rules for community-onset (CO) and hospital-onset (HO) suspected bloodstream infections.
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