The intrinsically disordered, amyloidogenic protein Tau associates with diverse classes of molecules, including proteins, nucleic acids, and lipids. Mounting evidence suggests that fatty acid molecules could play a role in the dysfunction of this protein, however, their interaction with Tau remains poorly characterized.
Titolo: | Unsaturated Fatty Acid-Induced Conformational Transitions and Aggregation of the Repeat Domain of Tau |
Autori: | ASSFALG, Michael (Corresponding) |
Data di pubblicazione: | 2020 |
Rivista: | |
Abstract: | The intrinsically disordered, amyloidogenic protein Tau associates with diverse classes of molecules, including proteins, nucleic acids, and lipids. Mounting evidence suggests that fatty acid molecules could play a role in the dysfunction of this protein, however, their interaction with Tau remains poorly characterized. |
Handle: | http://hdl.handle.net/11562/1020474 |
Appare nelle tipologie: | 01.01 Articolo in Rivista |
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