Nonalcoholic fatty liver disease (NAFLD) is common in older patients with type 2 diabetes. In older patients with type 2 diabetes, the presence of NAFLD is associated with a higher risk of hepatic (eg, nonalcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma) and extrahepatic (eg, cardiovascular disease, sarcopenia, and dementia) complications than that observed in other patient groups. For this reason, appropriate identification and management of NAFLD are clinically relevant particularly in the group of older patients with type 2 diabetes. In this regard, clinicians should consider the peculiar characteristics of elderly patients, such as frailty, multimorbidity, and polypharmacy.

Nonalcoholic Fatty Liver Disease and Implications for Older Adults with Diabetes

Mantovani, Alessandro;Targher, Giovanni;Zoppini, Giacomo
2020-01-01

Abstract

Nonalcoholic fatty liver disease (NAFLD) is common in older patients with type 2 diabetes. In older patients with type 2 diabetes, the presence of NAFLD is associated with a higher risk of hepatic (eg, nonalcoholic steatohepatitis, cirrhosis, and hepatocellular carcinoma) and extrahepatic (eg, cardiovascular disease, sarcopenia, and dementia) complications than that observed in other patient groups. For this reason, appropriate identification and management of NAFLD are clinically relevant particularly in the group of older patients with type 2 diabetes. In this regard, clinicians should consider the peculiar characteristics of elderly patients, such as frailty, multimorbidity, and polypharmacy.
2020
Elderly
NAFLD
NASH
Nonalcoholic fatty liver disease
Type 2 diabetes
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1020384
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