Mitotic perturbations frequently lead to chromosome mis-segregation that generates genome instability, thereby triggering tumor onset and/or progression. Error-free mitosis depends on fidelity-monitoring systems that ensure the temporal and spatial coordination of chromosome segregation. Recent investigations are focused on mitotic DNA damage response (DDR) and chromosome mis-segregations with the aim of developing more e
Titolo: | Depletion of trichoplein (TpMs) causes chromosome mis-segregation, DNA damage and chromosome instability in cancer cells. |
Autori: | D'Arca, Domenico (Corresponding) |
Data di pubblicazione: | 2020 |
Rivista: | |
Handle: | http://hdl.handle.net/11562/1020012 |
Appare nelle tipologie: | 01.01 Articolo in Rivista |
File in questo prodotto:
File | Descrizione | Tipologia | Licenza | |
---|---|---|---|---|
2020 Lauriola Cancers.pdf | Documento in Pre-print | ![]() | Open Access Visualizza/Apri |
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.