Herein, the fabrication of multi-responsive and hierarchically organized nano- material using core-shell SrF2 upconverting nanoparticles, doped with Yb3þ, Tm3þ, Nd3þ incorporated into gelatin methacryloyl matrix, is reported. Upon 800 nm excitation, deep monitoring of 3D-printed constructs is demonstrated. Addition of magnetic self-assembly of iron oxide nanoparticles within the hydrogel provides anisotropic structuration from the nano- to the macro-scale and magnetic responsiveness permitting remote manipulation. The present study provides a new strategy for the fabrication of a novel highly organized multi-responsive material using additive manufacturing, which can have important implications in biomedicine.
A Multifunctional Nanocomposite Hydrogel for Endoscopic Tracking and Manipulation
Cortelletti, Paolo;Speghini, Adolfo
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2020-01-01
Abstract
Herein, the fabrication of multi-responsive and hierarchically organized nano- material using core-shell SrF2 upconverting nanoparticles, doped with Yb3þ, Tm3þ, Nd3þ incorporated into gelatin methacryloyl matrix, is reported. Upon 800 nm excitation, deep monitoring of 3D-printed constructs is demonstrated. Addition of magnetic self-assembly of iron oxide nanoparticles within the hydrogel provides anisotropic structuration from the nano- to the macro-scale and magnetic responsiveness permitting remote manipulation. The present study provides a new strategy for the fabrication of a novel highly organized multi-responsive material using additive manufacturing, which can have important implications in biomedicine.
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