Objective. During the last decade, the role of complement system activation in the pathogenesis of antiphospholipid syndrome (APS) has been debated but an evident correlation with the proinflammatory and procoagulant phenotype in this disease has never been found. We carried out a retrospective study on APS women to evaluate the expression of some soluble and local complement and coagulation molecules supposed to be involved in promoting thrombotic events and pregnancy-related clinical complications.

Proteomic analysis of biological material from women with antiphospholipid syndrome. A retrospective study.

UGOLINI, Sara
2016-01-01

Abstract

Objective. During the last decade, the role of complement system activation in the pathogenesis of antiphospholipid syndrome (APS) has been debated but an evident correlation with the proinflammatory and procoagulant phenotype in this disease has never been found. We carried out a retrospective study on APS women to evaluate the expression of some soluble and local complement and coagulation molecules supposed to be involved in promoting thrombotic events and pregnancy-related clinical complications.
2016
9788869250088
antiphospholipid syndrome
complement system
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/950325
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