Recreational use of ketamine is increased over recent years in many parts of the world, and physical harms and addiction have been reported in heavily users (Morgan & Curran, 2012; Schifano et al., 2006). Initially confined to certain subcultures, ketamine is now the fourth most popular drug among UK clubbers after cannabis, ecstasy and cocaine, suggesting high potential of abuse (Morgan & Curran, 2012). This abuse potential can be related to its complex psychoactive profile observed at low doses, that include analgesic, psychotropic and antidepressant effects. Recent research has shown that ketamine can induce long lasting effects just after a single low dose acute administration.
Mechanisms of ketamine -induced neuroplasticity: potential effects on brain and behaviour
TEDESCO, Vincenzo;CHIAMULERA, Cristiano
2015-01-01
Abstract
Recreational use of ketamine is increased over recent years in many parts of the world, and physical harms and addiction have been reported in heavily users (Morgan & Curran, 2012; Schifano et al., 2006). Initially confined to certain subcultures, ketamine is now the fourth most popular drug among UK clubbers after cannabis, ecstasy and cocaine, suggesting high potential of abuse (Morgan & Curran, 2012). This abuse potential can be related to its complex psychoactive profile observed at low doses, that include analgesic, psychotropic and antidepressant effects. Recent research has shown that ketamine can induce long lasting effects just after a single low dose acute administration.
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