Polymorphism of mitochondrial DNA by means of restriction endonucleases analysis has been studied in two sardinian isolates, formerly subjected to different selective pressure due to malaria. The mitochondrial DNA haplotype frequencies differ significantly between the two villages. An evaluation of variability through Wahlund variance analysis rules out selective factors and suggests drift.
Mitochondrial DNA polymorphism analyzed by restriction endonucleases in two sardinian populations
SARTORIS, Silvia;
1985-01-01
Abstract
Polymorphism of mitochondrial DNA by means of restriction endonucleases analysis has been studied in two sardinian isolates, formerly subjected to different selective pressure due to malaria. The mitochondrial DNA haplotype frequencies differ significantly between the two villages. An evaluation of variability through Wahlund variance analysis rules out selective factors and suggests drift.
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