Gastrectomy with extended (D2) lymphadenectomy is the standard surgical approach not only in advanced gastric cancer but also in submucosal early gastric cancer. D2 lym-phadenectomy can improve the survival of patients with gastric cancer, but it requires sur-gical expertise to keep post-operative morbidity and mortality at low levels. The Japanese Clinical Oncology Group (JCOG) trial showed that extension of lymphadenectomy to para-aortic nodes does not improve the survival of patients with advanced gastric cancer. Never-theless, whether para-aortic node dissection is of benefit in selected groups of patients re-mains a matter of debate, since the 5-year survival of patients with metastases to para-aortic nodes is not negligible.
Gastric cancer: standard or extended lymphadenectomy ?
DE MANZONI, Giovanni;VERLATO, Giuseppe
2011-01-01
Abstract
Gastrectomy with extended (D2) lymphadenectomy is the standard surgical approach not only in advanced gastric cancer but also in submucosal early gastric cancer. D2 lym-phadenectomy can improve the survival of patients with gastric cancer, but it requires sur-gical expertise to keep post-operative morbidity and mortality at low levels. The Japanese Clinical Oncology Group (JCOG) trial showed that extension of lymphadenectomy to para-aortic nodes does not improve the survival of patients with advanced gastric cancer. Never-theless, whether para-aortic node dissection is of benefit in selected groups of patients re-mains a matter of debate, since the 5-year survival of patients with metastases to para-aortic nodes is not negligible.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.