Gastrectomy with extended (D2) lymphadenectomy is the standard surgical approach not only in advanced gastric cancer but also in submucosal early gastric cancer. D2 lym-phadenectomy can improve the survival of patients with gastric cancer, but it requires sur-gical expertise to keep post-operative morbidity and mortality at low levels. The Japanese Clinical Oncology Group (JCOG) trial showed that extension of lymphadenectomy to para-aortic nodes does not improve the survival of patients with advanced gastric cancer. Never-theless, whether para-aortic node dissection is of benefit in selected groups of patients re-mains a matter of debate, since the 5-year survival of patients with metastases to para-aortic nodes is not negligible.

Gastric cancer: standard or extended lymphadenectomy ?

DE MANZONI, Giovanni;VERLATO, Giuseppe
2011

Abstract

Gastrectomy with extended (D2) lymphadenectomy is the standard surgical approach not only in advanced gastric cancer but also in submucosal early gastric cancer. D2 lym-phadenectomy can improve the survival of patients with gastric cancer, but it requires sur-gical expertise to keep post-operative morbidity and mortality at low levels. The Japanese Clinical Oncology Group (JCOG) trial showed that extension of lymphadenectomy to para-aortic nodes does not improve the survival of patients with advanced gastric cancer. Never-theless, whether para-aortic node dissection is of benefit in selected groups of patients re-mains a matter of debate, since the 5-year survival of patients with metastases to para-aortic nodes is not negligible.
9788847023178
Limited lymphadenectomy; extended lymphadenectomy; superextended lymphadenectomy; Dutch trial; British trial; Taiwanese single-institution trial
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/11562/478558
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