Psoriasis is an immune-mediated chronic infl ammatory disease triggered and maintained by diff erent infl ammatory mediators, in which innate as well as adaptive immunity is crucial in the initiation and maintenance of psoriatic plaques. But the evolution of a psoriatic lesion is based on complex interplay between environmental, immunologic and genetic factors that sets the scene for disease initiating and maintenance events.
PSORIASIS
GISONDI, Paolo;
2012-01-01
Abstract
Psoriasis is an immune-mediated chronic infl ammatory disease triggered and maintained by diff erent infl ammatory mediators, in which innate as well as adaptive immunity is crucial in the initiation and maintenance of psoriatic plaques. But the evolution of a psoriatic lesion is based on complex interplay between environmental, immunologic and genetic factors that sets the scene for disease initiating and maintenance events.
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