Improving tractography using anatomical priors and multimodal integration

Incorporating anatomical knowledge and alternative modalities is crucial to accurately estimate white matter architecture. Several techniques have been developed to improve tractography algorithm precision, leveraging high-resolution anatomical images alongside anatomical constraints, tissue segmentation, and cortical surface modeling. Additionally, microstructural information and functional imaging can further regularize tractography trajectory and enhance structural connectivity measures. This study details how these methods provide unique insights that simplify the overall complexity of reconstructing the brain's structural network.