Purpose: To investigate human telomerase mRNA in the serum of prostate cancer patients. Experimental Design: The aim of this study was to investigate the telomerase mRNA detection in the serum of patients with a prostate tumour by using Real-Time reverse transcription PCR. The results were compared with biological samples obtained by age-matched normal donors. Results: Our data demonstrated that telomerase mRNA is detectable in the serum of patients with different prostate tumours whereas it is not amplifiable in normal donors. Conclusions: This marker, revealed with the molecular method of quantitative PCR in serum, may be useful for diagnosing and monitoring prostate cancer patients. © 2009 Nova Science Publishers, Inc. All rights reserved.
Telomerase mRNA detection in serum of patients with prostate cancer
Dalle Carbonare, L.
;Valenti, M. T.;
2009-01-01
Abstract
Purpose: To investigate human telomerase mRNA in the serum of prostate cancer patients. Experimental Design: The aim of this study was to investigate the telomerase mRNA detection in the serum of patients with a prostate tumour by using Real-Time reverse transcription PCR. The results were compared with biological samples obtained by age-matched normal donors. Results: Our data demonstrated that telomerase mRNA is detectable in the serum of patients with different prostate tumours whereas it is not amplifiable in normal donors. Conclusions: This marker, revealed with the molecular method of quantitative PCR in serum, may be useful for diagnosing and monitoring prostate cancer patients. © 2009 Nova Science Publishers, Inc. All rights reserved.
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