The chapter describes in summary the main mechanism of pain based on peripheral receptors and biochemical mediators. The pathways of pain and the central nervous system centers for pain are described. Different and the current hypothesis of pain modulation, sensitization, and manipulation are described. The concept of pain matrix based on the modern functional neuromaging in humans is reported. The descending control of brainstem on spinal mechanisms and the importance of attention and cognitive state on pain perception and elaboration are described.
Mechanisms of pain
Tamburin, Stefano
2019-01-01
Abstract
The chapter describes in summary the main mechanism of pain based on peripheral receptors and biochemical mediators. The pathways of pain and the central nervous system centers for pain are described. Different and the current hypothesis of pain modulation, sensitization, and manipulation are described. The concept of pain matrix based on the modern functional neuromaging in humans is reported. The descending control of brainstem on spinal mechanisms and the importance of attention and cognitive state on pain perception and elaboration are described.
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