Sfoglia per Autore
Cooperative antitumor and antiangiogenic activity after oral administration of a novel taxane, an antisense targeting protein kinase A and the EGF receptor inhibitor Iressa
2001-01-01 Damiano, V.; Caputo, R.; Fontanini, G.; Faviana, P.; Melisi, Davide; De Placido, S.; Zunino, F.; Bianco, A. R.; Ciardiello, F.; Tortora, Giampaolo
Oral administration of a novel taxane, an antisense oligonucleotide targeting protein kinase A, and the epidermal growth factor receptor inhibitor Iressa causes cooperative antitumor and antiangiogenic activity.
2001-01-01 Tortora, Giampaolo; R., Caputo; V., Damiano; G., Fontanini; Melisi, Davide; B. M., Veneziani; F., Zunino; A. R., Bianco; F., Ciardiello
A selective cyclooxygenase-2 inhibitor combined with the epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) ZD1839 ('Iressa') and protein kinase A antisense causes cooperative tumor growth inhibition after oral administration
2002-01-01 Tortora, Giampaolo; Caputo, R.; Damiano, V.; Melisi, Davide; Bianco, R.; Fontanini, G.; Bianco, A. R.; Ciardiello, F.
Zoledronic acid (ZOMETA) in combination with a COX-2 inhibitor and gefitinb ('Iressa, ZD1839') cooperatively inhibits growth and angiogenic factor expression and secretion in breast and prostate carcinoma cells
2003-01-01 Melisi, Davide; Caputo, R.; Caputo, R.; Bianoc, R.; Bianco, A. R.; Ciardiello, F.; Tortora, Giampaolo
Gefitinib ('Iressa, ZD1839') and a second generation antisense targeting murine double minute 2 (Mdm2) synergistically inhibit tumor growth and angiogenesis in hormone-refractory prostate cancer
2003-01-01 Bianco, R.; Caputo, R.; Caputo, R.; Damiano, V.; Melisi, Davide; Bianco, R.; Ciardiello, F.; Tortora, Giampaolo
Combination of a selective cyclooxygenase-2 inhibitor with EGFR tyrosine kinase inhibitor ZD1839 (‘Iressa’) and Protein Kinase A antisense causes a cooperative antitumor and antiangiogenic effect
2003-01-01 Tortora, Giampaolo; Caputo, R; Damiano, V; Caputo, R; Melisi, Davide; Bianco, R; Fontanini, G; Veneziani, Bm; DE PLACIDO, S; Bianco, Ar; Ciardiello, F.
Zoledronic acid (ZOMETA) in combination with a COX-2 inhibitor and gefitinib ('Iressa') cooperatively inhibits growth and angiogenic factor expression in breast and prostate carcinoma cells.
2004-01-01 Melisi, Davide; Caputo, R.; Caputo, R.; Bianco, R.; Bianco, A. R.; Ciardiello, F.; Tortora, Giampaolo
Antitumor activity of ZD6474, a vascular endothelial growth factor receptor tyrosine kinase inhibitor, in human cancer cells with acquired resistance to antiepidermal growth factor receptor therapy.
2004-01-01 Ciardiello, F; Bianco, R; Caputo, R; Caputo, R; Damiano, V; Troiani, T; Melisi, Davide; DE VITA, F; S., DE PLACIDO; Bianco, Ar; Tortora, Giampaolo
Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model.
2004-01-01 Raben, D; Bianco, C; Damiano, V; Bianco, R; Melisi, Davide; Mignogna, C; Darmiento, Fp; Cionini, L; Bianco, Ar; Tortora, Giampaolo; Ciardiello, F; Bunn, P.
Angiogenesis: A target for cancer therapy.
2004-01-01 Tortora, Giampaolo; Melisi, Davide; Ciardiello, F.
Antitumor activity of ZD6126, a novel vascular-targeting agent, is enhanced when combined with ZD1839, an epidermal growth factor receptor tyrosine kinase inhibitor, and potentiates the effects of radiation in a human non-small cell lung cancer xenograft model.
2004-01-01 D., Raben; C., Bianco; V., Damiano; R., Bianco; Melisi, Davide; C., Mignogna; F. P., D'Armiento; L., Cionini; A. R., Bianco; Tortora, Giampaolo; F., Ciardiello; P., Bunn
Therapeutic integration of signal transduction targeting agents and conventional anti-cancer treatments.
2004-01-01 Melisi, Davide; T., Troiani; V., Damiano; Tortora, Giampaolo; F., Ciardiello
Human cancer cells with acquired resistance to anti-EGFR therapy are inhibited by VEGF- and EGFR-receptors tyrosine kinase inhibitor ZD6474
2004-01-01 Bianco, R.; Caputo, R.; Caputo, R.; Damiano, V.; Troiani, T.; Melisi, Davide; Bianco, A. R.; Tortora, Giampaolo; Ciardiello, F.
A novel modified CpG inhibits EGF receptor signalling and synergistically enhances antitumor activity of cetuximab and irinotecan in colon cancer xenografts.
2005-01-01 Tortora, Giampaolo; Bianco, R.; Caputo, R.; D'Armiento, F.; Melisi, Davide; Bianco, A. R.; De Placido, S.; Agrawal, S.; Ciardiello, F.; Damiano, V.
AGENTI BIOLOGICI e CHEMIOTERAPICI: INTEGRAZIONE
2005-01-01 Tortora, Giampaolo; Melisi, Davide
Zoledronic acid cooperates with a cyclooxygenase-2 inhibitor and gefitinib in inhibiting breast and prostate cancer.
2005-01-01 Melisi, Davide; Caputo, R; Damiano, V; Bianco, R; Veneziani, Bm; Bianco, Ar; DE PLACIDO, S; Ciardiello, F; Tortora, Giampaolo
Cooperative antitumor effect of multitargeted kinase inhibitor ZD6474 and ionizing radiation in glioblastoma.
2005-01-01 Damiano, V; Melisi, Davide; Bianco, C; Raben, D; Caputo, R; Fontanini, G; Bianco, R; Ryan, A; Bianco, Ar; S., DE PLACIDO; Ciardiello, F; Tortora, Giampaolo
A novel modified CpG agonist of TLR-9 inhibits EGF receptor signalling and synergistically enhances antitumor activity of cetuximab and irinotecan eradicating colon cancer xenografts
2005-01-01 Tortora, Giampaolo; Bianco, R.; Caputo, R.; D'Armiento, F.; Melisi, Davide; Bianco, A. R.; De Placido, S.; Agrawal, S.; Ciardiello, F.; Damiano, V.
The protein kinase C beta antagonist enzastaurin (LY317615.HCl) inhibits cancer cell growth by multiple mechanisms and is active in EGFR inhibitors-resistant cancer cells
2006-01-01 Bianco, R.; Damiano, V.; Gelardi, T.; Daniele, G.; Caputo, R.; Melisi, Davide; Bianco, A. R.; Lahn, M; Ciardiello, F; Tortora, Giampaolo
Key cancer cell signal transduction pathways as therapeutic targets.
2006-01-01 Bianco, R; Melisi, Davide; Ciardiello, F; Tortora, Giampaolo
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