Anti-IgLON5 disease is a rare neurodegenerative tauopathy that displays heterogeneity in clinical spectrum, disease course, cerebrospinal fluid (CSF) findings, and variable response to immunotherapy. Sleep disorders, bulbar dysfunction, and gait abnormalities are common presenting symptoms, and conventional brain MRI scanning is often unrevealing.
Hypothalamic-Bulbar MRI hyperintensity in Anti-IgLON5 disease with serum-restricted antibodies: a case report and systematic review of literature
Tagliapietra, Matteo;Cardellini, Davide;Mariotto, Sara;Ferrari, Sergio;Zanusso, Gianluigi;Monaco, Salvatore
2021-01-01
Abstract
Anti-IgLON5 disease is a rare neurodegenerative tauopathy that displays heterogeneity in clinical spectrum, disease course, cerebrospinal fluid (CSF) findings, and variable response to immunotherapy. Sleep disorders, bulbar dysfunction, and gait abnormalities are common presenting symptoms, and conventional brain MRI scanning is often unrevealing.
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