Colorectal carcinomas (CRCs) with a micropapillary pattern and those showing high counts of poorly differentiated clusters (PDCs) are characterized by a higher probability to develop nodal metastases and have a worse prognosis. In light of the morphologic similarity to the micropapillary component, we aimed to verify whether PDCs also display an inverted secretory pattern.

Micropapillary pattern and poorly differentiated clusters represent the same biological phenomenon in colorectal cancer: a proposal for a change in terminology

Barresi, Valeria;
2014-01-01

Abstract

Colorectal carcinomas (CRCs) with a micropapillary pattern and those showing high counts of poorly differentiated clusters (PDCs) are characterized by a higher probability to develop nodal metastases and have a worse prognosis. In light of the morphologic similarity to the micropapillary component, we aimed to verify whether PDCs also display an inverted secretory pattern.
2014
Colorectal cancer; E-cadherin; MUC1; Micropapillary; Poorly differentiated clusters; Tumor budding; Adenocarcinoma; Aged; Aged, 80 and over; Biomarkers, Tumor; Cadherins; Colorectal Neoplasms; Female; Humans; Male; Middle Aged; Mucin-1; Prognosis
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/987786
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