Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system. Although inflammatory lesions of the white matter are the hallmark of the disease, several neuropathological and imaging studies have clearly confirmed that the grey matter is not spared by the disease. The most recent data suggest that a chronic meningeal inflammation leads to a subpial demyelination resulting in a surface-in gradient of neuronal loss. This article is protected by copyright. All rights reserved.

Multiple sclerosis and epilepsy: much more than a coincidence

Calabrese, Massimiliano
2018-01-01

Abstract

Multiple sclerosis (MS) is a chronic autoimmune demyelinating disease of the central nervous system. Although inflammatory lesions of the white matter are the hallmark of the disease, several neuropathological and imaging studies have clearly confirmed that the grey matter is not spared by the disease. The most recent data suggest that a chronic meningeal inflammation leads to a subpial demyelination resulting in a surface-in gradient of neuronal loss. This article is protected by copyright. All rights reserved.
2018
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/982893
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