As baseline, total T lymphocytes, T helper, T suppressor, B lymphocytes and Natural Killer cells, were reduced vs. normal range in 24%, 33%, 24%, 59% and null of patients, respectively.A second blood sample was withdrawn after 14-58 days (mean 36) from starting RT, in which we found significantly increased the patients damaged up to 66%, 65%, 62%, 88% and 7% (p=< 0,0001 for each LS ). Compared with the nadir of LS depletion, at 44 (5-180) and 153 (43-130) days from the completion of RT, all the LS raised significantly, except for a weak value of T Helper category (p=0,0145 and 0,0226 respectively).
Changes in peripheral lymphocyte subpopulations following radiation therapy
G Capodaglio;E Guizzardi;E Nicolis;
2017-01-01
Abstract
As baseline, total T lymphocytes, T helper, T suppressor, B lymphocytes and Natural Killer cells, were reduced vs. normal range in 24%, 33%, 24%, 59% and null of patients, respectively.A second blood sample was withdrawn after 14-58 days (mean 36) from starting RT, in which we found significantly increased the patients damaged up to 66%, 65%, 62%, 88% and 7% (p=< 0,0001 for each LS ). Compared with the nadir of LS depletion, at 44 (5-180) and 153 (43-130) days from the completion of RT, all the LS raised significantly, except for a weak value of T Helper category (p=0,0145 and 0,0226 respectively).
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