The blood to anticoagulant ratio is standardized according to the physiological calcium concentration in blood samples conventionally used for hemostasis testing. Specifically, one fixed volume of 0.109 mmol/L sodium citrate is added to 9 volumes of blood. Since little is known about the impact of hypercalcemia on the calcium-binding capacity of citrate, this study was planned to investigate the effect of experimental hypercalcemia on routine hemostasis testing.

Impact of experimental hypercalcemia on routine haemostasis testing

LIPPI, Giuseppe;SALVAGNO, GIAN LUCA;GELATI, Matteo;DANESE, Elisa;
2017-01-01

Abstract

The blood to anticoagulant ratio is standardized according to the physiological calcium concentration in blood samples conventionally used for hemostasis testing. Specifically, one fixed volume of 0.109 mmol/L sodium citrate is added to 9 volumes of blood. Since little is known about the impact of hypercalcemia on the calcium-binding capacity of citrate, this study was planned to investigate the effect of experimental hypercalcemia on routine hemostasis testing.
2017
Citrate, Hemostasis, Coagulation
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/960008
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