The vertebrate limb is a classical model for understanding patterning of three-dimensional structures during embryonic development. Although decades of research have elucidated the tissue and molecular interactions within the limb bud required for patterning and morphogenesis of the limb, the cellular and molecular events that shape the limb bud itself have remained largely unknown.

WNT5A/JNK and FGF/MAPK pathways regulate the cellular events shaping the vertebrate limb bud

FUMENE FERUGLIO, Paolo;
2010-01-01

Abstract

The vertebrate limb is a classical model for understanding patterning of three-dimensional structures during embryonic development. Although decades of research have elucidated the tissue and molecular interactions within the limb bud required for patterning and morphogenesis of the limb, the cellular and molecular events that shape the limb bud itself have remained largely unknown.
2010
Animals; Body Patterning; Cell Movement; Chick Embryo; Embryo, Mammalian; Embryonic Development; Female; Fibroblast Growth Factors; JNK Mitogen-Activated Protein Kinases; Limb Buds; Mice; Morphogenesis; Wnt Proteins; MAP Kinase Signaling System
File in questo prodotto:
Non ci sono file associati a questo prodotto.

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/938281
Citazioni
  • ???jsp.display-item.citation.pmc??? 83
  • Scopus 132
  • ???jsp.display-item.citation.isi??? 123
social impact