Lipids are essential for many biological processes and crucial in the pathogenesis of several diseases. The transport of such poorly water-soluble metabolites is often mediated by lipid-binding proteins. Understanding the chemistry of ligand binding to intracellular lipid carriers sets the basis for the development of new drugs.
Autori: | |
Data di pubblicazione: | 2011 |
Titolo: | Protein-mediated lipid transport: from molecular recognition to drug design |
Autori: | Assfalg M. |
Numero degli autori: | 1 |
Lingua: | Italiano Inglese |
Supporto: | STAMPA |
Parole Chiave: | proteins; lipid transport; NMR |
Abstract: | Lipids are essential for many biological processes and crucial in the pathogenesis of several diseases. The transport of such poorly water-soluble metabolites is often mediated by lipid-binding proteins. Understanding the chemistry of ligand binding to intracellular lipid carriers sets the basis for the development of new drugs. |
Appare nelle tipologie: | 01.01 Articolo in Rivista |
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