Purpose: Acute cardiovascular events are related to type of coronary plaque rather than coronary artery stenosis degree. The aim of our study is to evaluate the prevalence of sub-clinic coronary artery disease (CAD) and relate plaque composition to carotid US and MRI. Methods and Materials: 30 consecutive patients (22 M, 8 F) mean age 67 ± 8 YO between 03 and 06/2010 underwent MDCT-CA and carotid artery US and MRI. All patients were on high level pre-test probability of CAD according to AHA risk score. For carotid arteries and coronaries type of plaque (calcific, mixed and fibrolipidic) and degree of stenosis was distinguished into significant (>50% lumen narrowing) or not significant (<50% lumen narrowing). Correlation of plaque composition and significance of stenosis was obtained by means of Spearman correlation. Results: 38 plaques (1.26/patient) were detected with US and MRI (27/38 fibrolipidic/mixed, 11/38 calcific). Mean Ca score obtained was 2205.5 (0-2893.8). 105 plaques were detected in MDCT-CA fibrolipidic (20/105) 19 % mixed 29/105 (28%) and calcific 56/105 (53%). Correlation between US and MRI in plaque morphology was high (r = 0.95 for mixed, r = 1 for calcified and r = 0.8 for soft plaques). Correlation between the two MRI and MDCT-CA was r = 0.311, P = 0.101 for fibrolipidic plaque, r = 0.579, P = 0.001 for mixed plaque, r = 0.471, P = 0.010 for calcific plaque. Correlation for stenosis degree and between MRI and US was r = 0.8 and between the MDCT. CA and MRI technique was r = 0.518 P = 0.004. Conclusions: Plaque morphology and pattern of stenosis on carotid arteries can help to predict the presence of significative CAD.
Prognostic value of subclinic artery disease: correlation between MDCT-CA and carotid artery MRI
MALAGO', Roberto;FRATTA PASINI, Anna Maria;POZZI MUCELLI, Roberto
2011-01-01
Abstract
Purpose: Acute cardiovascular events are related to type of coronary plaque rather than coronary artery stenosis degree. The aim of our study is to evaluate the prevalence of sub-clinic coronary artery disease (CAD) and relate plaque composition to carotid US and MRI. Methods and Materials: 30 consecutive patients (22 M, 8 F) mean age 67 ± 8 YO between 03 and 06/2010 underwent MDCT-CA and carotid artery US and MRI. All patients were on high level pre-test probability of CAD according to AHA risk score. For carotid arteries and coronaries type of plaque (calcific, mixed and fibrolipidic) and degree of stenosis was distinguished into significant (>50% lumen narrowing) or not significant (<50% lumen narrowing). Correlation of plaque composition and significance of stenosis was obtained by means of Spearman correlation. Results: 38 plaques (1.26/patient) were detected with US and MRI (27/38 fibrolipidic/mixed, 11/38 calcific). Mean Ca score obtained was 2205.5 (0-2893.8). 105 plaques were detected in MDCT-CA fibrolipidic (20/105) 19 % mixed 29/105 (28%) and calcific 56/105 (53%). Correlation between US and MRI in plaque morphology was high (r = 0.95 for mixed, r = 1 for calcified and r = 0.8 for soft plaques). Correlation between the two MRI and MDCT-CA was r = 0.311, P = 0.101 for fibrolipidic plaque, r = 0.579, P = 0.001 for mixed plaque, r = 0.471, P = 0.010 for calcific plaque. Correlation for stenosis degree and between MRI and US was r = 0.8 and between the MDCT. CA and MRI technique was r = 0.518 P = 0.004. Conclusions: Plaque morphology and pattern of stenosis on carotid arteries can help to predict the presence of significative CAD.
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
