Gentamicin and Vancomycin are released from cements at inhibitory concentrations in the infection site for prolonged periods. The comination of gentamicin and vancomycin exert an effective inhibition against multiresistant bacteria. Spacers seem an adeguate system for antibiotic delivery in prosthetic infections in two-stage revision for infected total hip or knee replacements
Release of antibiotics and inhibitory activity in drainage fluids following temporary implants in two-stage revision surgery
BERTAZZONI MINELLI, Elisa;BENINI, Anna;Magnan, Bruno;BARTOLOZZI, Pietro
2005-01-01
Abstract
Gentamicin and Vancomycin are released from cements at inhibitory concentrations in the infection site for prolonged periods. The comination of gentamicin and vancomycin exert an effective inhibition against multiresistant bacteria. Spacers seem an adeguate system for antibiotic delivery in prosthetic infections in two-stage revision for infected total hip or knee replacements
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