Hepatocellular carcinoma (HCC) is a major health problem, being the fifth most common cancer worldwide with 626,000 new cases in 2002 [1]. The incidence and absolute mortality of HCC is increasing in Europe and the United States [2], and is currently the leading cause of death amongst cirrhotic patients [3,4]. Improvement of the overall outcome of these patients will come from prevention policies, early detection programs and advancement in the efficacy of therapies. Identification of the at-risk populations is particularly crucial to implement efficient prevention policies, and to engage the adequate populations in costeffective surveillance programs. Thus, the impact of the knowledge of at-risk populations in the surveillance strategy, and the relevance of these factors for the prevention and treatment strategies should be carefully analyzed.
Risk factors for hepatocellular carcinoma in HCV cirrhosis: what we know and what is missing.
FATTOVICH, Giovanna;
2006-01-01
Abstract
Hepatocellular carcinoma (HCC) is a major health problem, being the fifth most common cancer worldwide with 626,000 new cases in 2002 [1]. The incidence and absolute mortality of HCC is increasing in Europe and the United States [2], and is currently the leading cause of death amongst cirrhotic patients [3,4]. Improvement of the overall outcome of these patients will come from prevention policies, early detection programs and advancement in the efficacy of therapies. Identification of the at-risk populations is particularly crucial to implement efficient prevention policies, and to engage the adequate populations in costeffective surveillance programs. Thus, the impact of the knowledge of at-risk populations in the surveillance strategy, and the relevance of these factors for the prevention and treatment strategies should be carefully analyzed.I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.