Effect of Antioxidant Therapy on Oxidative Stress In Vivo

Over the last few decades, many efforts have been put into fields that explore the potential benefits of antioxidants, especially with regards to aging, cancer, cardiovascular diseases, and neurodegenerative diseases. However, despite the positive results in experimental studies, there is no clear evidence of clinical benefit of antioxidant supplementation. In this Editorial we summarize the results of the studies that contributed to the Special Issue “ Effect of Antioxidant therapy on oxidative stress in vivo” . All studies emphasized the potential usefulness of antioxidant supplementation in different pathological situations, while also highlighting the need for further in vitro and in vivo studies.