The mechanisms driving primary progressive and relapsing-remitting multiple sclerosis (PPMS/RRMS) phenotypes are unknown. Magnetic resonance imaging (MRI) studies support the involvement of gray matter (GM) in the degeneration, highlighting its damage as an early feature of both phenotypes. However, the role of GM microstructure is unclear, calling for new methods for its decryption.

Unraveling the MRI-Based Microstructural Signatures Behind Primary Progressive and Relapsing-Remitting Multiple Sclerosis Phenotypes

Boscolo Galazzo, Ilaria;Brusini, Lorenza
;
Cruciani, Federica;Pitteri, Marco;Ziccardi, Stefano;Bajrami, Albulena;Castellaro, Marco;Pizzini, Francesca B;Calabrese, Massimiliano;Menegaz, Gloria
2022-01-01

Abstract

The mechanisms driving primary progressive and relapsing-remitting multiple sclerosis (PPMS/RRMS) phenotypes are unknown. Magnetic resonance imaging (MRI) studies support the involvement of gray matter (GM) in the degeneration, highlighting its damage as an early feature of both phenotypes. However, the role of GM microstructure is unclear, calling for new methods for its decryption.
2022
SVM
3D-SHORE
EDSS
diffusion MRI
gray matter
morphometry
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/11562/1045542
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