Large-scale epidemiological data on vascular disorders of the intestine

Objectives: This article aims to provide updates on the worldwide epidemiology of vascular disorders of the intestine.Methods: A comprehensive search for obtaining worldwide epidemiologic information on the burden of vascular disorders of the intestine was carried out in the Global Health Data Exchange (GHDx) repository. The condition 'vascular intestinal disorders' was associated with other epidemiologic variables such as year, sex, age, location and socioeconomic status.Results: The current global incidence and mortality of vascular disorders of the intestine are 8.11 per 100,000 cases/year and 1.26 per 100,000 deaths/year, respectively, translating into a death rate of 15.5%. Both global incidence and mortality are 32% higher in the female sex and have both displayed a continuous increase during the past 20 years (+29.3% and +18.4% since 1998, respectively). Incidence and mortality curves appear similar between sexes, with the incidence increasing after the age of 40 years and mortality after the age of 50 years, respectively. The peak of both worldwide incidence and mortality was seen in very elderly people. The death rate increased in parallel with incidence and mortality, from ∼1% to 3% in childhood up to ∼50% after the age of 95 years. Both incidence and mortality displayed a positive association with socioeconomic status. Future projections suggest that incidence and mortality will display 44% and 24% growths by the year 2050.Conclusions: Our analysis demonstrates that the clinical and societal burden of vascular disorders of the intestine is especially higher in women, in the elderly and in people with higher socioeconomic status.